Pigmented Lesions of the Oral Mucosa Pocket Dentistry Happy Wednesday! , In this video, a patients labial melanotic macule (a benign pigmented lesion) is being treated with liquid nitrogen. Labial melanotic macules are flat and asymmetrical with a Female 44 year old patient with ORAL MELANOMA in tongue with a 2 year disease length. The malignant melanoma of the oral cavity is a neoplasia developed from melanocytic cells that are in the Case of melanotic macule in a 46 F Let's review ORAL MELANOTIC MACULE FOCAL MELANOSIS . The oral melanotic macule is a flat, brown, mucosal discoloration produced by a focal increase in melanin Got a black spot on my tongue. Not sure what it is. Should I be worried?. Full article Pigmented macule on the tongue of a 12 year old girl Journal of the American Academy of Dermatology