Psychiatry.org Vaping is Unhealthy. Tips and Resources to Help Quit. Vaping Health Effects of Vaping Smoking and Tobacco Use CDC Electronic Nicotine Delivery Systems (ENDS), including e cigarettes and vapes, are often perceived as a safer alternative to traditional tobacco. But is the evidence really supporting this belief? A recent umbrella review published Ban on vaping: reality check or turf war? RTD Nonnicotine vapes may be marketed as safe, but many still contain chemicals, have unknown health effects, and aren't FDAregulated. Teens are using them more ofteneven alongside nicotine vapes. No ecigarette is risk free.