Hotel Vape Detectors: Complete Guide to Combating Vaping Do Hotels Have Vape Detectors? Nexlar Security Can hotels detect vaping in rooms? Vape Detectors Are Giving Students Their Bathrooms Back Does vaping set off smoke detectors in a hotel room? E CigaretteReviewsUK Your guests aren't the only ones checking in. So are their vape pens. With over 13 million regular vapers in the U.S. alone, unauthorized vaping is a major operational risk for hotels.